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| 性 别： |
女 |
出生年月： |
1978-08-31 |
| 职 称： |
教授 |
工作单位： |
文理学院化学系 |
| 硕导（招生学科）： |
化学 |
博导（招生学科）： |
化学生物学/生物与医药 |
| 办公电话： |
0451-55190930 |
E-mail： |
gaoshuang@neau.edu.cn |
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| 课程编号 |
课程名称 |
课程类别 |
学时 |
| 20600038j |
仪器分析 |
公共课 |
32 |
| 111213 |
药物分析技术 |
博士必修课 |
32 |
| 109324 |
生物仪器分析 |
博士选修课 |
32 |
| 211232 |
高等仪器分析 |
硕士必修课 |
32 |
| 主持科研项目概况 |
主要开展纳米农药创制的研究工作，利用超分子自组装及静电纺丝技术建立具有靶标导向与控释功能的新型智能响应纳米载药系统，通过纳米传输系统的应用改善难溶活性物质的分散性、控制释放速率、提高农药的生物利用率。
1、 国家自然科学基金，31801784，基于ALS除草剂的取代磺酰胺二氮（氧）杂二环类安全剂设计、合成及活性研究，2019/01-2021/12，24万元，结题，主持
2、 黑龙江省自然科学基金联合重点项目，ZL2024C003，智能刺激响应性纳米农药体系的构建及对靶释放机制研究，2025.1-2028.12，50万元，在研，主持
3、 山东中新科农，技术开发横向课题，新型纳米纤维农药制剂的研发，2024.09-2027.08，在研，主持
4、 黑龙江省“优秀青年教师基础研究支持计划”立项项目，YQJH2023189，靶向递送的智能刺激响应性纳米农药的构建及对靶识别机制的研究，2023.01-2025.12 ，20万元，在研，主持
5、 黑龙江省博士后科研启动金，LBH-Q21076，农用超分子纳米纤维的创制与研究，2021.09-2024.09 ，6万元，在研，主持
6、 哈尔滨市科技创新人才基金，2017RAQXJ017、新型取代氧氮杂桥环类安全剂的设计、合成与构效研究，2017/09-2019/08，10万元，结题，主持
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| 项目获奖概况 |
1. 基于分子碎片重组设计的农用功能分子及其作用机制研究，2020.黑龙江省科学技术奖，二等奖（4）
2. 安全剂保护作物免受除草剂药害研究，2016. 08, 黑龙江省科学技术奖，二等奖（4）
3. 安全剂保护作物免受除草剂药害研究，2016.02, 年黑龙江省农业科技奖，一等奖（4） |
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| 代表性著作、论文 |
1.Guang Yang, Fengrui Li, Haoru Zhang, Honglei Yan, Shuang Gao*, Ying Fu*, Fei Ye*, Electrospinning for producing antifungal nanofibers consisting of prochloraz/hydroxypropyl-γ-cyclodextrin inclusion complex. Industrial Crops & Products, 2024, 211:118282. （SCI）IF=5.9 (一区) （高被引论文，热点论文）
2.Zhang Y H, Li F R, Guo G H , Xiu Y ,Yan H L, Zhao L X, Gao S*,Ye F* , Fu Y*.Preparation and characterization of betulin/methyl-beta-cyclodextrin inclusion complex electrospun nanofiber: Improving the properties of betulin. Industrial Crops & Products, 2024, 209:117974. （SCI）IF=5.9 (一区) （高被引论文，热点论文）
3.Shuang Gao, Lei Zong, Yuhang Zhang, Lixia Zhao , Fei Ye *, Ying Fu*,Antifungal pentachloronitrobenzene/hydroxypropyl-beta-cyclodextrin inclusion complex nanofibers by electrospun with no polymer: Fabrication and characterization. Journal of Cleaner Production. 2023, 413, 137499（SCI）IF=11.1 (一区) （高被引论文）
4.Weiwei Feng , Xinyu Guo , Guang Yang , Yao Yao , Lixia Zhao , Shuang Gao *, Fei Ye *, Ying Fu *Direct electrospinning for producing multiple activity nanoffbers consisting of aggregated luteolin/hydroxypropyl-gamma-cyclodextrin inclusion complex. International Journal of Biological Macromolecules.2024, 270,132344. （SCI）IF=8.2 (一区)
5.Liu, B, Duan, J, Zhang, Y, Wang, R, Zhao, L, Gao, S*, Ye, F, Fu, Y. Preparation and characterization of hexaconazole/hydroxypropyl-gamma-cyclodextrin inclusion complex nanofibers for sustainable agriculture: Improved physicochemical properties and antifungal activity of hexaconazole. Journal of Molecular Structure. 2024, 1299, 137195. （SCI）IF=3.8 (二区)
6.Shuang Gao , Weiwei Feng, Han Sun, Lei Zong, Xiaoming Li , Lixia Zhao , Fei Ye *, Ying Fu*, Fabrication and Characterization of Antifungal Hydroxypropyl-beta Cyclodextrin/ Pyrimethanil Inclusion Compound Nanofibers Based on Electrospinning Journal of Agricultural and Food Chemistry，2022 70 (26), 7911-7920（SCI）IF=5.895 (一区)
7.Shuang Gao , Xiaoming Li , Guang Yang , Weiwei Feng , Lei Zong , Lixia Zhao , Fei Ye *, Ying Fu Antibacterial perillaldehyde/hydroxypropyl-gamma-cyclodextrin inclusion complex electrospun polymer-free nanofiber: Improved water solubility, thermostability, and antioxidant activity. Industrial Crops & Products. 2022, 176: 114300（SCI）IF=6.449 (一区)
8.Shuang Gao, Xiaoming Li, Jingyu Jiang, Lixia Zhao, Ying Fu, Fei Ye, Fabrication and Characterization of Thiophanate methylHydroxypropyl-beta-cyclodextrin Inclusion Complex Nanofibers by Electrospinning. Journal of Molecular Liquids, 2021, 335：116228 （SCI）IF=6.633 (二区)
9.Gao, S; Liu, YY; Jiang, JY; Li, XM; Zhao, LX; Fu, Y; Ye, F. Encapsulation of thiabendazole in hydroxypropyl-beta-cyclodextrin nanofibers via polymer-free electrospinning and its characterization, Pest Management Science, 2020,76(9): 3264-3272, IF=4.845 (一区) （高被引论文）
10.Shuang Gao, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu1* and Lixia Zhao. An Environmentally Safe Formulation with Enhanced Solubility and Fungicidal Activity: Self-assembly and Characterization of Difenoconazole-β-CD Inclusion Complex. Journal of Molecular Liquids, 2021, 327：114874 （SCI）IF=6.633 (二区) （高被引论文）
11.Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu* and Lixia Zhao, Thiram/hydroxypropyl-beta-cyclodextrin inclusion complex electrospun nanofibers for a fast dissolving water-based drug delivery system. Colloids and Surfaces B: Biointerfaces, 2021, 201: 111625. （SCI）IF=5.999 (二区)（高被引论文）
12.Shuang Gao, Jingyu Jiang, Xiaoming Li, Fei Ye*, Ying Fu1* and Lixia Zhao.Electrospun Polymer-Free Nanofibers Incorporating Hydroxypropyl-beta-cyclodextrin/Difenoconazole via Supramolecular Assembly for Antifungal Activity. Journal of Agricultural and Food Chemistry 2021, 69, 5871−5881（SCI）IF=5.895 (一区)
13.Shuang Gao, Jingyu Jiang, Xiaoming Li, Yanyan Liu, Lixia Zhao, Ying Fu, Fei Ye. Enhanced physicochemical properties and herbicidal activity of an environment-friendly clathrate formed by β-cyclodextrin and herbicide cyanazine. Journal of Molecular Liquids, 2020,305, 112858.（SCI）IF=6.165 (二区)
14.Gao, S.; Jiang, J.-Y.; Liu, Y.-Y.; Fu, Y.; Zhao, L.-X.; Li, C.-Y.; Ye, F. Enhanced Solubility, Stability, and Herbicidal Activity of the Herbicide Diuron by Complex Formation with β-Cyclodextrin. Polymers 2019, 11, 1396. （SCI）IF=3.164 (二区)
15.Shuang Gao, Yan-Yan Liu, Jing-Yu Jiang, Ying Fu, Li-Xia Zhao, Chun-Yan Li and Fei Ye. Protective Responses Induced by Chiral 3-Dichloroacetyl Oxazolidine Safeners in Maize (Zea mays L.) and the Detoxification Mechanism. Molecules 2019, 24, 3060;（SCI）IF=3.060 (三区)
16.Gao, S.; Bie, C.; Ji, Q.Y.; Ling, H.Y.; Li, C.Y.; Fu, Y.; Zhao, L.X.; Ye, F., Preparation and characterization of cyanazine–hydroxypropyl-beta-cyclodextrin inclusion complex. RSC Adv. 2019, 9, 26109-26115. （SCI）IF=3.049 (三区)
17.Gao, S.; Liu, Y. Y.; Jiang, J. Y.; Ji, Q. Y.; Fu, Y.; Zhao, L. X.; Li, C. Y.; Ye, F. Physicochemical properties and fungicidal activity of inclusion complexes of fungicide chlorothalonil with β-cyclodextrin and hydroxypropyl-β-cyclodextrin. Journal of Molecular Liquids, 2019, 293, 111513.（SCI）IF=4.564 (二区)
18.Shuang Gao, Chao Bie, Yanyan Liu, Tianyu Zhang, Ying Fu and Fei Ye*.Functional Supramolecular of Inclusion Complex of Herbicide Fluroxypyr with HPβCD. Polymers, 2018, 10, 1294（SCI）IF=3.364 (二区)
19.Gao Shuang, Wang Yuxin, Jiang Bin, Fu Ying*. Application of problem-based learning in instrumental analysis teaching at Northeast Agricultural University. Analytical and Bioanalytical Chemistry，2018, 410(16):3621-3627（SCI）IF=3.307
20.Fei Ye ; Hai-Feng Cao; Li-Na Wei; Chen Wang; Ying Fu; Chun-Yan Li; Shuang Gao*. Chiral 3-dichloroacetyl oxazolidines induced the activity of enzymes in maize for the detoxified herbicide, International Journal of Agriculture and Biology，2018,20,1027-1032（SCI）
21.Fei YE, Hai-Feng Cao, Xue-Song Chen, Meng ZHANG, Ying FU, Chun-Yan LI and Shuang GAO*.Effects of chiral 3-dichloroacetyl oxazolidine on glutathione S-transferase and antioxidant enzymes activity in maize treated with acetochlor，Tarim Bilimleri Dergisi-Journal of Agricultural Sciences. 2018,24(3): 422-429（SCI）
22.Gao, Shuang ; Bie, Chao; Chen, Xue-Song; Zhao, Li-Xia; Fu, Ying; Li,Chun-Yan; Ye, Fei *. Inducing Glutathione S-Transferase Expression and Activity using an Herbicide Safener against Metolachlor in Maize , International Journal of Agriculture and Biology, 2017, 19(6): 1357-1362.（SCI）
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| 授权的专利等情况 |
1.高爽，刘波，付颖，闫红蕾，郭欣雨一种柚皮素环糊精包合物纳米纤维及其制备方法和应用ZL202211720892.3
2.高爽，李晓明，叶非，冯卫伟 一种紫苏醛纳米纤维及其制备方法和应用 ZL20211012996.3
3.付颖，叶非，高爽 一种含有喹喔啉结构的三酮类化合物、制备方法及其应用 ZL 201911193040.1
4.付颖，叶非，高爽 一种含肉桂酰基的三酮类化合物、制备方法及其应用 ZL201911191742.6
5.叶非，付颖，赵李霞，高爽 用于玉米生长的区域防治有害杂草的除草组合物及其用途 ZL201810750196.4 |
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| 其他获奖及荣誉称号 |
| 黑龙江省化学学会理事，
黑龙江省分析测试学会理事，
东北农业大学“东农学者计划”高层次人才杰出学者，
黑龙江省自然科学基金评审专家，
教育部学位中心学位论文评审专家
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