基本信息
 付颖
性 别: 出生年月: 1973-09-03
职 称: 教授 工作单位: 应用化学系
硕导(招生学科): 化学 博导(招生学科): 化学生物学
办公电话: 55191507 E-mail: fuying@neau.edu.cn
 开设课程情况
课程编号 课程名称 课程类别 学时
20600005g 普通化学 基础课 56
20600021g 有机化学 基础课 56
 主持科研项目概况

1.        氟啶虫酰胺衍生物合成新技术、新产品、新工艺的研究开发,委托方:山东中新科农生物技术有限公司,2022.12.28-2024.12,到账经费 26万,(在研)

2.        黑龙江省自然基金重点项目:基于药效团重组设计的多靶点白化除草剂的合成及分子作用机制研究(ZD2022C003),2022.10-2025.1050万(在研)

3.        国家自然科学基金,基于天然产物分子碎片重组设计的新型HPPD抑制剂的合成及分子作用机制研究(22077014),2021.1-2024.1263万(在研)

4.        国家自然科学基金,基于药效团拼接设计的新型HPPD抑制剂的合成、除草活性及QSAR研究(31772208),2018.1-2021.1260万(在研)

5.        哈尔滨市杰出青年基金,新型抑制HPPD型除草剂的创制(2015RAYXJ010),2016.1-2017.1230万(结题)

6.        黑龙江省自然科学基金,取代哌啶三酮类HPPD抑制剂的合成及除草活性研究B201303),2014.1-2016.125万(结题)

7.        国家自然科学基金,苯并吡(噁)嗪类安全剂的设计、合成及构效关系研究311014732012.1-2014.1223万(结题)

8.        黑龙江省博士后科研启动基金,新型取代芳甲酰基喹啉酮HPPD抑制剂的合成及活性研究,(LBH-Q12151),2013.1-2014.125万(结题)

9.        黑龙江省教育厅科学技术研究项目,二氯乙酰基苯并噁嗪解毒酰胺类除草剂药害作用机理研究(12521015),2012.1-2014.122万(结题)

10.    哈尔滨市科技创新人才研究专项资金项目,酰胺类除草剂安全剂的合成及解毒机理研究2012RFQXN015),2012.1-2014.123万(结题)

11.    东北农业大学博士启动基金,苯并噁嗪类安全剂的设计、合成及构效关系研究,2011-20136万(结题)

12.    中国博士后基金,苯并噁嗪类安全剂的合成、解毒机制及构效关系研究(20100471243),2010.1-2011.123万(结题)

13.    黑龙江省青年基金项目,脂肪酸合成抑制剂解毒剂的合成、解毒机制及构效关系研究(QC2009C44),2010.1-2012.124万(结题)

14.    黑龙江省博士后基金,乙酰辅酶A抑制剂胁迫影响玉米的生理机制及化学修复研究,2009-2011(LBH-Z09253)(结题)

15.    黑龙江省教育厅研究项目,果蔬中有机磷农药快速降解方法的研究与应用11521032),2007.1-2009.12(结题)

16.    哈尔滨市科技创新人才研究专项资金项目,乙酰辅酶A抑制剂的安全剂的合成、解毒机制及构效关系研究(2007RFQXN017),2007.1-2009.12(结题)

17.    黑龙江省教育厅研究项目,基于东北植物资源绿色农药的研究(10531021),2003.1-2005.12(结题)

 项目获奖概况

1.        黑龙江省青年科技奖,2017

2.        哈尔滨市青年科技奖,2016

3.        基于分子碎片重组设计的农用功能分子及其作用机制研究,黑龙江省科技二等奖2020,第一名

4.        安全剂保护作物免受除草剂药害研究,黑龙江省科技二等奖2016,第一名

5.        安全剂保护作物免受除草剂药害研究,黑龙江省农业科技一等奖2016,第一名

6.        除草剂污染土壤的生物修复及作物保护,黑龙江省科技二等奖2015,第二名

7.        除草剂污染土壤的生物修复及作物保护,黑龙江省高校科学技术二等奖2015,第二名

8.        付颖,黑龙江省首届优秀博士后出站报告奖,苯并吡(噁)嗪类安全剂的合成及解毒机制研究,2013

9.        基于磺酰脲类除草剂的安全剂活性与构效研究,黑龙江省科技三等奖, 2006,第二名

10.    基于磺酰脲类除草剂的安全剂活性与构效研究,黑龙江省高校科学技术二等奖2006,第二名

11.    除草剂解毒剂(安全剂)二氯乙酰胺合成与生测研究,黑龙江省教育厅科技二等奖,2001第四名

 代表性著作、论文

1. Bing-Bing Lu, Zhi-Xin Xing, Yong-Shun Bao, Fei Ye*, Ying Fu*, Selective Luminescent Sensing of Teflubenzuron and Oxyfluorfen by a Resorcin[4]arene- Based Metal-Organic Framework, Chemical Engineering Journal, 2023, 452, 139234 doi: https://doi.org/10.1016/j.cej.2022.139234 (一区)

2. Ling Jia, Li-Xia Zhao, Fang Sun, Jie Peng, Jia-Yu Wang, Xin-Yu Leng, Shuang Gao, Ying Fu*, Fei Ye*, Diazabicyclo derivatives as safeners protect cotton from injury caused by flumioxazin, Pesticide Biochemistry and Physiology, 2022, 187 105185, https://doi.org/10.1016/j.pestbp.2022.105185 (一区)

3. Shuang Gao, Weiwei Feng, Han Sun, Lei Zong, Xiaoming Li, Lixia Zhao, Fei Ye*, Ying Fu*, Fabrication and Characterization of Antifungal Hydroxypropyl-β-Cyclodextrin/Pyrimethanil Inclusion Compound Nanofibers Based on Electrospinning, Journal of Agricultural and Food Chemistry, 2022, 70, 7911-7920, https://doi.org/10.1021/acs.jafc.2c01866 (一区)

4. Jia-Yu Wang, Shuang Gao, Juan Shi, Hai-Feng Cao, Tong Ye, Ming-Li Yue, Fei Ye*, Ying Fu*, Virtual screening based on pharmacophore model for developing novel HPPD inhibitors, Pesticide Biochemistry and Physiology, 2022, 184, 105109, https://doi.org/10.1016/j.pestbp.2022.105109 (一区)

5. Ling Jia, Xin-Yu Jin, Li-Xia Zhao, Ying Fu*, Fei Ye*, Research Progress in the Design and Synthesis of Herbicide Safeners: A Review, Journal of Agricultural and Food Chemistry, 2022, 70, 5499-5515,https://doi.org/10.1021/acs.jafc.2c01565 (一区)

6. Li-Xia Zhao, Jian-Feng Peng, Feng-Yi Liu, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*, Discovery of novel phenoxypyridine as promising protoporphyrinogen IX oxidase inhibitors, Pesticide Biochemistry and Physiology, 2022, 184, 105102, https://doi.org/10.1016/j.pestbp.2022.105102 (一区)

7. Li-Xia Zhao, Jian-Feng Peng, Feng-Yi Liu, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*, Design, Synthesis, and Herbicidal Activity of Diphenyl Ether Derivatives Containing a Five-Membered Heterocycle, Journal of Agricultural and Food Chemistry, 2022, 70, 1003-1018, https://doi.org/10.1021/acs.jafc.1c05210 (一区)

8. Shuang Gao, Xiaoming Li, Guang Yang, Weiwei Feng, Lei Zong, Lixia Zhao, Fei Ye*, Ying Fu*, Antibacterial perillaldehyde/hydroxypropyl-γ-cyclodextrin inclusion complex electrospun polymer-free nanofiber: Improved water solubility, thermostability, and antioxidant activity, Industrial Crops & Products, 2022, 176, 114300,https://doi.org/10.1016/j.indcrop.2021.114300 (一区)

9. Yulong Liu, Lu Li, Mingli Yue, Liu Yang, Fang Sun, Guoqiang Xu, Ying Fu*, Ye Fei *, A switch-on fluorescent probe for detection of mesotrione based on the straight forward cleavage of carbon-nitrogen double bond of Schiff base, Chemical Engineering Journal, 2022, 430, 132758, DOI: https://doi.org/10.1016/j.cej.2021.132758 (一区)

10. Wei Hu, Shuang Gao, Li-Xia Zhao, Ke-Liang Guo, Jia-Yu Wang, Ying-Chao Gao, Xin-Xin Shao, Ying Fu*, Fei Ye*, Design, synthesis and biological activity of novel triketone-containing quinoxaline as HPPD inhibitor, Pest Management Science, 2022, 78, 938-946, DOI:10.1002/ps.6703 (一区)

11. Fang Sun, Liu Yang, Shijie Li, Yubo Wang, Ludi Wang, Ping Li, Fei Ye*, Ying Fu*, New fluorescent probes for the sensitive determination of glyphosate in food and environmental samples, Journal of Agricultural and Food Chemistry, 2021, 69, 12661-12673, DOI: https://doi.org/10.1021/acs.jafc.1c05246 (一区)

12. Hao-Min Song, Li-Xia Zhao, Shuai-Qi Zhang, Tong Ye, Ying Fu*, and Fei Ye*, Design, synthesis, structure-activity relationship, molecular docking, and herbicidal evaluation of 2-cinnamoyl-3-hydroxycyclohex-2-en-1-one derivatives as novel 4-hydroxyphenylpyruvate dioxygenase inhibitors, Journal of Agricultural and Food Chemistry, 2021, 69, 12621-12633, DOI: https://doi.org/10.1021/acs.jafc.1c04621 (一区)

13. Zi-Wei Wang, Li-Xia Zhao, Shuang Gao, Xin-Yu Leng, Yue Yu, Ying Fu*, Fei Ye*, Quinoxaline derivatives as herbicide safeners by improving Zea mays tolerance, Pesticide Biochemistry and Physiology, 2021, 178, 104958, DOI: https://doi.org/10.1016/j.pestbp.2021.104958 (一区)

14. Ling Jia, Shuang Gao, Yuan-Yuan Zhang, Li-Xia Zhao, Ying Fu*, Fei Ye*, Fragment recombination design, synthesis, and safener activity of novel ester-substituted pyrazole derivatives, Journal of Agricultural and Food Chemistry, 2021, 69: 8366-8379, DOI:https://doi.org/10.1021/acs.jafc.1c02221 (一区)

15. Li-Xia Zhao, Zhi-Xin Wang, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*, Phenoxypyridine derivatives containing natural product coumarins with allelopathy as novel and promising proporphyrin IX oxidase-inhibiting herbicides: Design, synthesis and biological activity study, Pesticide Biochemistry and Physiology, 2021, 177, 104897, DOI: https://doi.org/10.1016/j.pestbp.2021.104897 (一区)

16. Li-Xia Zhao, Zhi-Xin Wang, Jian-Feng Peng, Yue-Li Zou, Yong-Zhuo Hui, Yong-Zheng Chen, Shuang Gao, Ying Fu*, Fei Ye*, Design, synthesis, and herbicidal activity of novel phenoxypyridine derivatives containing natural product coumarin, Pest Management Science, 2021, 77, 4785-4798 DOI: 10.1002/ps.6523 (一区)

17. Shuang Gao, Jingyu Jiang, Xiaoming Li, Fei Ye,* Ying Fu*, and Lixia Zhao, Electrospun polymer-free nanofibers incorporating hydroxypropyl β-cyclodextrin/difenoconazole via supramolecular assembly for antifungal activity, Journal of Agricultural and Food Chemistry, 2021, 69, 5871−5881, DOI:https://doi.org/10.1021/acs.jafc.1c01351 (一区)

18. Yulong Liu, Liu Yang, Qing Bai, Wenbo Li, Yeqi Zhang, Ying Fu*, Fei Ye*, Highly efficient nondoped blue electroluminescence based on hybridized local and charge-transfer emitter bearing pyrene-imidazole and pyrene, Chemical Engineering Journal, 2021, 420, 129939, https://doi.org/10.1016/j.cej.2021.129939 (一区)

19. Ying Fu, Meng Wang, Li-Xia Zhao, Shuai-Qi Zhang, Yong-Xuan Liu, You-Yuan Guo, Dong Zhang, Shuang Gao, Fei Ye*. Design, synthesis, herbicidal activity and CoMFA of novel aryl-formyl piperidinone HPPD inhibitors, Pesticide Biochemistry and Physiology, 2021, 174, 104811, https://doi.org/10.1016/j.pestbp.2021.104811(高被引论文,热点论文)

20. Zi-Wei Wang, Li-Xia Zhao, Peng Ma, Tong Ye, Ying Fu*, Fei Ye*, Fragments recombination, design, synthesis, safener activity and CoMFA model of novel substituted dichloroacetylphenyl sulfonamide derivatives, Pest Management Science, 2021, 77, 1724-1738, DOI: https://doi.org/10.1002/ps.6193 (一区)

21. Tao Kang, Shuang Gao, Li-Xia Zhao, Yue Zhai, Fei Ye*, Ying Fu*, Design, synthesis, and SAR of novel 1,3-disubstituted imidazolidine or hexahydropyrimidine derivatives as herbicide safeners, Journal of Agricultural and Food Chemistry, 2021, 69: 45-54, DOI: https://doi.org/10.1021/acs.jafc.0c04436(高被引及热点论文)

22. Lu Li, Shuang Gao, Liu Yang, Yu-Long Liu, Ping Li, Fei Ye*, Ying Fu*, Cobalt (II) complex as a fluorescent sensing platform for the selective and sensitive detection of triketone HPPD inhibitors, Journal of Hazardous Materials, 2021, 404, 124015, DOI: https://doi.org/10.1016/j.jhazmat.2020.124015(高被引论文)

23. Yuan-Yuan Zhang, Shuang Gao, Minh-Tu Hoang, Zi-Wei Wang, Xin Ma, Yue Zhai, Na Li, Li-Xia Zhao, Ying Fu*, Fei Ye*, Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize, Pest Management Science, 2021, 77, 1, 177-183 DOI: https://doi.org/10.1002/ps.6005(高被引论文) (一区)

24. Ke-Liang Guo, Li-Xia Zhao, Zi-Wei Wang, Ying-Chao Gao, Juan-Juan Li, Shuang Gao, Ying Fu*, Fei Ye*, Design, Synthesis, and Bioevaluation of Substituted Phenyl Isoxazole Analogues as Herbicide Safeners, Journal of Agricultural and Food Chemistry, 2020, 68(39): 10550-10559 https://dx.doi.org/10.1021/acs.jafc.0c01867 (一区)

25. Li-Xia Zhao, Jia-Jun Hu, Zhi-Xin Wang, Min-Lei Yin, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*, Novel phenoxy-(trifluoromethyl)pyridine-2-pyrrolidinone- based inhibitors of protoporphyrinogen oxidase: Design, synthesis, and herbicidal activity, Pesticide Biochemistry and Physiology, 2020, 170, 104684, DOI:https://doi.org/10.1016/j.pestbp.2020.104684 (一区)

26. Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Lixia Zhao, Ying Fu*, Fei Ye*, Encapsulation of thiabendazole in hdroxypropyl-β-cyclodextrin nanofibers via polymer-free electrospinning and its characterization, Pest Management Science, 2020, 76: 3264–3272, DOI:10.1002/ps.5885(高被引论文)

27. Li-Xia Zhao, Mao-Jun Jiang, Jia-Jun Hu, Yue-Li Zou, Yuan Cheng, Tao Ren, Shuang Gao, Ying Fu*, and Fei Ye*, Design, synthesis, and herbicidal activity of novel diphenyl ether derivatives containing fast degrading tetrahydrophthalimide. Journal of Agricultural and Food Chemistry, 2020, 68(12), 3729-3741 https://dx.doi.org/10.1021/acs.jafc.0c00947(高被引论文)

28. Yuan-Yuan Zhang, Shuang Gao, Yong-Xuan Liu, Chen Wang, Li-Xia Zhao, Ying Fu*, Fei Ye*, Design, synthesis and biological activity of novel diazabicyclo derivatives as safeners. Journal of Agricultural and Food Chemistry, 2020, 68(11), 3403-3414, DOI:10.1021/acs.jafc.9b07449(高被引论文)

29. Liu Yang, Yu-Long Liu, Cheng-Guo Liu, Fei Ye, Ying Fu*, Two luminescent dye@MOFs systems as dual-emitting platforms for efficient pesticides detection, Journal of Hazardous Materials, 2020, 381, 120966(高被引论文)

30. Ying Fu, Dong Zhang, Shuai-Qi Zhang, Yong-Xuan Liu, You-Yuan Guo, Meng-Xia Wang, Shuang Gao, Li-Xia Zhao, Fei Ye*, Discovery of N-aroyl diketone/triketone derivatives as novel 4-hydroxyphenylpyruvatedioxygenase inhibiting-based herbicides, Journal of Agricultural and Food Chemistry, 2019, 67, 11839-11847(高被引论文)

31. Fei Ye, Yue Zhai, Ke-Liang Guo, Yong-Xuan Liu, Na Li, Shuang Gao, Li-Xia Zhao, Ying Fu*, Safeners improve maize tolerance under herbicide toxicity stress by increasing the activity of enzyme in vivo, Journal of Agricultural and Food Chemistry, 2019, 67, 11568-11576(高被引论文)

32. Ying Fu, Shuai-Qi Zhang, Yong-Xuan Liu, Jing-Yi Wang, Shuang Gao, Li-Xia Zhao, Fei Ye*, Design, synthesis, SAR and molecular docking of novel green niacintriketone HPPD inhibitor, Industrial Crops & Products, 2019, 137: 566-575(高被引论文及热点论文)

33. Fei Ye, Yue Zhai, Tao Kang, Shi-Long Wu, Juan-Juan Li, Shuang Gao, Li-Xia Zhao, Ying Fu*, Rational design, synthesis and structure-activity relationship of novel substituted oxazole isoxazole carboxamides as herbicide safener, Pesticide Biochemistry and Physiology, 2019, 157: 60-68. DOI: https://doi.org/10.1016/j.pestbp.2019.03.003(高被引论文)

34. Ying Fu, Kui Wang, Peng Wang, Jing-Xin Kang, Shuang Gao, Li-Xia Zhao, Fei Ye*, Design, synthesis and herbicidal activity evaluation of novel aryl-naphthyl methanone derivatives, Frontiers in Chemistry, 2019, 7: 2 doi: 10.3389/fchem.2019.00002(高被引论文)

 授权的专利等情况

1.        叶非,付颖,杨柳,刘豫龙,刘艳,“on-off”型荧光探针、其制备方法及其应用,专利号:ZL 2021 1 1500867.X申请日:2021.12.9,授权日:2022.8.5

2.        杨柳,叶非,付颖,刘豫龙,刘艳,“off-on”型离子检测荧光探针、离子检测试剂盒、制备方法及应用,专利号:ZL 2022 1 0080545.2申请日:2022.1.24,授权日:2022.6.21

3.        刘豫龙,付颖,叶非,杨柳,李璐,一种硫脲基修饰的在衍生物荧光探针及其制备方法和应用,专利号:ZL 202111193983.1申请日:2021.10.13,授权日:2022.5.24

4.        付颖,叶非,刘豫龙,杨柳,李璐,一种酰胺基芘衍生物荧光探针及其制备方法和应用,专利号:ZL 202111192723.2申请日:2021.10.13,授权日:2022.4.29

5.        付颖,叶非,高爽,郭科良,一种含有喹喔啉结构的三酮类化合物、制备方法及其应用,中国发明专利,专利号:ZL 201911193040.1申请日:2019.11.28,授权日:2020.11.24

6.        付颖,叶非,高爽,张帅琦,一种含肉桂酰基的三酮类化合物、制备方法及其应用,中国发明专利,专利号:ZL201911191742.6申请日:2019.11.28,授权日:2020.7.28

7.        叶非,付颖,赵李霞,高爽,吴世龙,用于玉米生长的区域防治有害杂草的除草组合物及其用途,中国发明专利,专利号:ZL201810750196.4,申请日:2018.07.10,授权日:2020.3.17

8.        付颖,叶非,赵李霞,陈文更,除草组合物及其应用,中国发明专利,专利号:ZL201711383039.6,申请日:2017.12.20,授权日:2020.3.17

9.        赵李霞,叶非,付颖,一种用于单子叶作物的除草组合物及其用途,中国发明专利,专利号:ZL 2015 1 1033695.4申请日:2015.12.28,授权日:2018.6.19

10.    付颖,叶非,赵李霞,康晶欣,王姣,一种用于禾本科作物田的除草剂及其用途,中国发明专利,专利号:ZL 2016 1 0078256.3申请日:2016.1.29授权时间:2018.1.30

11.    付颖,叶非,赵李霞,曲丽华N-二氯乙酰基-6,7-二氯-1,2,3,4-四氢喹喔啉及其制备方法中国发明专利,专利号:ZL 2013 1 0196037.1申请日:2013.5.24授权时间:2015.5.20

12.    叶非,白靖文,付颖,张鑫,用超声波法提取苦参碱的方法,中国发明专利,专利号:ZL200710071951.8,申请日:2007.3.28授权时间:2010.5.26

13.    叶非,付颖,李颖娇,一种N-二氯乙酰基噁唑烷类除草剂安全剂的制备方法专利号:ZL200710071894.3,申请日:2007.3.16授权时间:2009.8.12

14.    赵李霞,邹月利,付颖,陈成,佟晓芳,姜帆,一种沙棘冰酒及其制备方法,专利号:ZL201210185502.7,申请日:2012.6.7授权时间:2013.4.17

 

 其他获奖及荣誉称号

黑龙江省教学名师

黑龙江省教学新秀

黑龙江省师德师风先进个人

中国化工学会农药专业委员会委员

黑龙江省化学学会理事

黑龙江省化学学会副理事长

黑龙江省分析测试学会理事

中国化学会高级会员

黑龙江省专利奖评审专家